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LaGrange College is located in LaGrange, Georgia (pop. 30,000) — one hour southwest of Atlanta along I-85. An inviting community that combines small-town charm with big-city options, LaGrange is home to Fortune 500 companies, historic landmarks, unique shops and restaurants for every taste. Area entertainment ranges from live music and a 10-screen movie theater to West Point Lake and Callaway Gardens. Nearby Atlanta features a wealth of cultural and recreational opportunities, including professional sports and top concert venues. Atlanta also is a great place for internships and field experiences with organizations like CNN, Coca-Cola and the Atlanta Braves. And if you want to get away for a weekend road trip, you'll find Gulf Coast beaches and the Smoky Mountains just a few hours away.

A recent case of a 51 year old male with an interest in testosterone replacement illustrates the benefits of the multi-parametric prostate MRI scan. Noting a PSA value of only ng/ml; the digital rectal exam (DRE) identified an area of interest on the left side, albeit, it was not definitive for prostate cancer. Neither the gray scale ultrasound nor Color Flow Doppler ultrasound evaluation suggested any specific abnormality consistent with the area of interest previously identified on DRE. An MRI scan was suggested as the next best step in the evaluation. The scan isolated a region of interest on the left side at the Apex to Middle portion of the prostate gland concordant with the findings on the DRE.  Based upon the findings of the MRI scan, a targeted biopsy with 6 needle cores was recommended and implemented. An Antiandrogen was initiated pre-biopsy to mitigate against “needle tracking”. Specifically, an Antiandrogen selectively blocks the receptor on the prostate cell from attracting testosterone as it exits the capsule, thereby, disabling the cells in preparation for cell death or apoptosis. The Pathology evaluation revealed a grade of cancer that was amenable to being treated conservatively or focally. In this case, the failure to use a MRI scan would have exposed this patient to the possibility of missing the cancer altogether; associated with sampling bias, a very real possibility for needle tracking (assuming cancer was found), or worse yet, the go ahead to supplement with testosterone, when in fact, the cancer was missed. Using  testosterone in this scenario would have stimulated cancer cells to grow wildly, while causing the PSA to spike abnormally, thereby, making the diagnosis of prostate cancer – a potentially uncontrollable clinical event, albeit, avoidable. Given the expertise of a Urolologic consultation, this case turned out well. The patient is now contemplating a focal treatment with high intensity focused ultrasound with a plan to supplement with testosterone once his cancer has been cured. An inability to document the resolution of prostate cancer by a repeat MRI scan and/or a stable PSA post-operatively will preclude this patient from using testosterone replacement therapy.

Because the relationship between long-term androgen use and gynecological health is not yet fully understood, and because many trans men often experience embarrassment and/or access issues over obtaining ongoing gynecological care, some may feel it is appropriate to pursue such surgeries as a preventative measure. Always discuss the latest medical research and the pros and cons of these procedures with your doctor. For more information on hysterectomy, oophorectomy, PCOS, endometrial cancer, and ovarian cancer see the hysterectomy and oophorectomy page on this web site.

Tribulus Terrestis
Tribulus works by stimulating the anterior pituitary to produce Leutinizing Hormone. Tribulus is a first choice addition to many testosterone boosting formulas because it could keep natural levels testosterone not having any negative effects on its long term production. It is a well-documented risk to introduce exogenous hormonal substances (like steroids) that shut down the endogenous production of testosterone. As the use of these products tapers down, it is essential that the endogenous production kicks back in as soon as possible because normal levels of these hormones are needed to maintain much of the gains made while taking them., therefore tribulus becomes a valuable addition to any hormone boosting stack.

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Because the relationship between long-term androgen use and gynecological health is not yet fully understood, and because many trans men often experience embarrassment and/or access issues over obtaining ongoing gynecological care, some may feel it is appropriate to pursue such surgeries as a preventative measure. Always discuss the latest medical research and the pros and cons of these procedures with your doctor. For more information on hysterectomy, oophorectomy, PCOS, endometrial cancer, and ovarian cancer see the hysterectomy and oophorectomy page on this web site.

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