Testosteron hormone

Though you may already be aware of potential side effects from testosterone abuse (note I said abuse and not use), here they are again: lowered HDL-cholesterol levels (good cholesterol), testicular atrophy, reductions in sperm count, prostate enlargement, liver damage (primarily with oral steroids that have been modified with a 17-alkyl substitution), menstrual irregularities, suppression of endogenous hormone levels (like LH and T), development of palpable breast tissue in men (also known as gynecomastia), clitoral enlargement, and acne.

Testosterone increases lean body mass and decreases fat mass in young men; the magnitude of the changes induced by testosterone in lean and fat mass are correlated with testosterone dose and the prevalent testosterone concentrations. Older men are as responsive to the anabolic effects of testosterone on the muscle as young men, but have increased frequency of adverse events with higher testosterone doses. This reciprocal change in lean and fat mass induced by androgens is best explained by the hypothesis that androgens promote the commitment of mesenchymal pluripotent cells into myogenic lineage and inhibit adipogenesis through an androgen receptor mediated pathway. Resident muscle satellite cells increase in number with testosterone administration forming myoblasts leading to greater numbers of myonuclei in larger myofibers. Testosterone administration is associated with increased size of motor neurons. The roles of 5-alpha reduction and aromatization of testosterone into dihydrotestosterone and estradiol, respectively, in mediating testosterone effects on body composition are poorly understood.

In women a cream preparation is used most commonly.  It contains estradiol, the most active form of estrogen, and often estriol, a weaker estrogen considered to be protective against breast cancer.  This combination is called Biest, usually in a ratio of four parts estriol to one part estradiol.  Initially the cream is applied both in the morning and at night.  Later, and in older women, it can be used just once a day.  It may be combined with progesterone in the same preparation for convenience and cost-saving.  It may also be combined with testosterone.  Transdermal testosterone, however, may cause hair growth where it is applied, so we usually recommend it to be applied to the thighs where it is less evident and more easily handled.

10. Sleep and Fatigue . Inadequate testosterone can also lead to poor sleep quality, which means that the only thing you'll want to do under the covers is put your head on the pillow and crash.  Testosteorne deficiencies decrease the all-important recuperative REM sleep and other critical sleep parameters. One study showed that low T did this not only by increasing weight gain, which negatively impacts sleep in and of itself, but also through other mechanisms that we do not yet understand. [11] And none of this should be a surprise considering how much that testosterone affects the brain.

Testosteron hormone

testosteron hormone

10. Sleep and Fatigue . Inadequate testosterone can also lead to poor sleep quality, which means that the only thing you'll want to do under the covers is put your head on the pillow and crash.  Testosteorne deficiencies decrease the all-important recuperative REM sleep and other critical sleep parameters. One study showed that low T did this not only by increasing weight gain, which negatively impacts sleep in and of itself, but also through other mechanisms that we do not yet understand. [11] And none of this should be a surprise considering how much that testosterone affects the brain.

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