One study appeared to show that gw 50156 side effects included the growth of cancer cells but on further inspection, the results could be considered misleading. The study of gw1516 which was carried out on mice included 1000 times the recommended dose, taken over a prolonged period of time. As no individual would be taking such an inflated level of gw501516, there is debatable value attached to this particular study. Nevertheless, despite the criticism of this study, it was sufficient for GSK to drop the project so shouldn’t be dismissed completely.
Inclusion criteria are characteristics that the prospective subjects must have if they are to be included in the study, while exclusion criteria are those characteristics that disqualify prospective subjects from inclusion in the study. Inclusion and exclusion criteria may include factors such as age , sex , race , ethnicity , type and stage of disease , the subject’s previous treatment history, and the presence or absence (as in the case of the “healthy” or “control” subject) of other medical, psychosocial, or emotional conditions.