Tibolone has tissue -selective estrogenic effects, with desirable effects in bone , the brain , and the vagina , and lack of undesirable action in the endometrium and breasts .  Its tissue selectivity is the result of metabolism , enzyme modulation (., of estrogen sulfatase and estrogen sulfotransferase ), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as tamoxifen , which produce their tissue-selectivity via means of modulation of the ER.   As such, to distinguish it from SERMs, tibolone has been described as a "selective tissue estrogenic activity regulator" (STEAR),  and also as a "selective estrogen enzyme modulator" (SEEM). 
Boldenone acetate is popularly called “short acting Equipoise.” In fact, it is a veterinary steroid that is most known for use in horse racing, and it has never been approved for human use. However, boldenone acetate is a somewhat widespread injectable anabolic steroid among steroid dramatically increases protein synthesis and red blood cell count meaning that nutrients are transported throughout the body much more effectively. Boldenone Acetate can be effectively incorporated in both “cutting” and “bulking” cycles due to the well balanced effects of this anabolic substance. Boldenone Acetate aromatizes very little, and therefore produces almost no estrogenic side effects such as water retention or “gyno”.For the dosage,recommend Dose like most Aces 200-500mg PW. Max 800mg. It will kick in about 3 days. Half life 3 days.